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What may interact with Zanaflex?

Do not take Zanaflex with any of the following medications:

• ciprofloxacin
• clonidine
• fluvoxamine
• guanabenz
• guanfacine
• methyldopa

Zanaflex may also interact with the following medications:

• acyclovir
• alcohol
• antihistamines
• baclofen
• barbiturates like phenobarbital
• benzodiazepines
• cimetidine
• famotidine
• female hormones, like estrogens or progestins and birth control pills
• medicines for high blood pressure
• medicines for irregular heartbeat
• medicines for pain like codeine, morphine, and hydrocodone
• medicines for sleep
• rofecoxib
• some antibiotics like levofloxacin, ofloxacin
• ticlopidine
• zileuton

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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